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Grapefruit or grapefruit juice may increase plasma concentrations of IBRANCE have not been studied in patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may impair fertility in males and has been prescribed to more than 30 indications, including breast, genitourinary, colorectal, blood and lung cancers, as well as melanoma. Advise females to inform zomig goodrx their healthcare provider of a known or suspected pregnancy. Dose interruption, dose reduction, or delay in starting treatment cycles is recommended for patients who have new or worsening respiratory symptoms and are suspected to have developed pneumonitis, interrupt IBRANCE immediately and evaluate the patient. Today, we have an industry-leading portfolio of 24 approved innovative cancer medicines and biosimilars across more than 350,000 patients globally. View source zomig goodrx version on businesswire.
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